alveolar rhabdomyosarcoma การใช้

Translocation of this gene with PAX3 has been associated with alveolar rhabdomyosarcoma.
It is expressed at higher levels in alveolar rhabdomyosarcoma than in embryonal rhabdomyosarcoma.
The pathologic differential diagnosis is the grouping of small-blue-round-cell tumors, which includes lymphoma, alveolar rhabdomyosarcoma, and desmoplastic small round cell tumor, among others.
The specific function of the paired box gene 7 is unknown but speculated to involve tumor suppression since fusion of this gene with a forkhead domain family member has been associated with alveolar rhabdomyosarcoma.